Research Group of Neuromodulation and Epilepsy

Eötvös Loránd University, SUC, BDTTC, Department of Biology; HUNGARY, Szombathely




LAB MEMBERS

  • Team Member

    DR. ZSOLT KOVÁCS PHD, HABIL.
    Group Leader

    Status: associate professor
    Affiliation: Eötvös Loránd University, SUC, BDTTC, Department of Biology, Károlyi Gáspár tér 4., 9700 Szombathely, Hungary
    kovacs.zsolt@sek.elte.hu
    CV
    Research interests: Pathomechanism of absence epilepsy; nutritional (metabolic) therapies for CNS diseases; distribution and functions of nucleosides in the brain.
    Methods: In vivo electrophysiology and pharmacology, EEG recording; behavioral tests (e.g., EPM and LDB).

    Team Member

    DR. ILDIKÓ KÉRI-SCHMIDTHOFFER, PHD
    Lab member

    Status: senior lecturer

    Affiliation: Eötvös Loránd University, SUC, BDTTC, Department of Biology, Károlyi Gáspár tér 4., 9700 Szombathely, Hungary

    keri.schmidthoffer.ildiko@sek.elte.hu

    Research interests: The role of genes and gene expression in the life mechanisms of cells.

    Methods: DNA and RNA extraction, agarose gel electrophoresis, RT-PCR.

    Team Member

    ENIKŐ RAUCH, MSC
    Lab member

    Status: PhD student of University of Pécs (supervisor: Dr. Zsolt Kovács, Eötvös Loránd University, Savaria University Centre, Department of Biology; Szombathely, Hungary).
    Affiliation: University of Pécs, Faculty of Sciences, Institute of Biology; H-7624 Pécs, Ifjúság útja 6., Hungary.
    Place and theme of PhD research work: Eötvös Loránd University, Savaria University Centre, Department of Biology; Effects of ketone supplements on absence epileptic activity (2023 - ).
    raucheniko9810@gmail.com
    Research interests: Investigation of nucleosides- and ketone supplements-evoked effects on absence epileptic activity.
    Methods: EEG recording on freely moving animals.

  • Team Member

    BRIGITTA BRUNNER, MSC
    Lab member

    Status: PhD student of University of Pécs (supervisor: Dr. Zsolt Kovács, Eötvös Loránd University, Savaria Campus, Department of Biology; Szombathely, Hungary).
    Affiliation: University of Pécs, Faculty of Sciences, Institute of Biology; H-7624 Pécs, Ifjúság útja 6., Hungary.
    Place and theme of PhD research work: Eötvös Loránd University, Savaria Campus, Department of Biology; Effects of ketone supplements on absence epileptic activity (2019 - ).
    brunnerb28[@]gmail.com
    Research interests: Ketone supplements-evoked alleviating influences on central nervous system diseases.
    Methods: EEG recording on freely moving rats.

    Team Member

    RENÁTA LAKATOS, PhD
    Former Lab member

    reni.lakatos[@]gmail.com
    Research interests: Investigation of pathomechanism of absence epilepsy: effects of non-adenosine nucleosides on absence epileptic activity in WAG/Rij rats.
    Methods: EEG recording on freely moving animals.

    Team Member

    LIST OF BSC AND MSC STUDENTS

    Enikő Rauch (2021-2023)
    Edina Gartner (2012-2014)
    Szabina Hídvégi (2012-2014)
    Viktória Lábas (2006-2008)
    Edit Zátonyiné Novák (2006-2008)
    Zsuzsanna Tallérné Adi (2006-2008)
    Boglárka Lengyel (2006-2008)
    Beáta Kovács (2005-2007)
    Gyöngyi Patonainé Tóth (2005-2007)
    Krisztián Kadlicskó (2005-2007)
    Tamás Török (2004-2005)
    Írisz Császár (2003-2005)
    Eszter Júlia Papp (2002-2004)
    László Treutz (2001-2003)
    Éva Szakács (2001-2003)
    Gabriella Vágner (2001-2003)
    Eszter Magán (2000-2002)


MAIN COLLABORATING PARTNERS

  • Team Member

    DR. DOMINIC P. D’AGOSTINO, PHD

    Status: associate professor
    Affiliation: University of South Florida, Morsani College of Medicine; Department of Molecular Pharmacology and Physiology, University of South Florida, 12901 Bruce B. Downs Blvd. MDC8, Tampa, FL 33612, USA; Institute for Human and Machine Cognition, Ocala, FL, USA
    dpd500@yahoo.com
    WEB
    Research interests: Development and testing of metabolic-based therapies and drugs that target pathways linked pathophysiologically with seizure disorders, neurodegenerative diseases, metabolic dysregulation, cancer, muscle wasting and motor performance.
    Methods: Radio-telemetry (EEG, EMG), electrophysiology; fluorescence, confocal, electron and atomic force microscopy; histology; biochemical assays, metabolomics; toxicology; in vivo bioluminescence imaging; spectrophotometry; behavioral and motor function testing.

    Team Member

    DR. CSILLA ARI D’AGOSTINO, PHD

    Status: research assistant professor
    Affiliation: University of South Florida, Department of Psychology, Hyperbaric Neuroscience Research Laboratory, 12901 Bruce B. Downs Blvd. MDC8, Tampa, FL 33612, USA
    csari2000[@]yahoo.com
    WEB
    Research interests: Psychological and physiological adaptations to extreme environments (underwater, high altitude); metabolic therapies for neurological diseases and cancer, using ketogenic diet, exogenous ketone supplementation and hyperbaric oxygen.
    Methods: Cognitive and motor function tests; light, fluorescence and confocal microscopy; histology; biochemical assays, metabolomics; in vivo bioluminescence imaging; hyperbaric oxygen treatment.

    Team Member

    DR. LÁSZLÓ HÉJA, PHD

    Status: senior research fellow
    Affiliation: Chemical Biology Research Group, HUN-REN Research Centre for Natural Sciences; a H-1117 Budapest
    heja.laszlo@ttk.hu
    WEB
    Research interests: Exploration of the role of astrocytes in modulating neuronal function in the healthy and diseased brain; identification of potentially druggable (primarily astrocytic) target proteins or mechanisms in pathophysiological conditions.
    Methods: In vivo and in vitro simultaneous fluorescent imaging and electrophysiology.




GOALS AND EQUIPMENT

PUBLICATIONS

full papers

 

  1. Kovács, Z., Rauch, E., D’Agostino, D.P., Ari, C. (2024). Putative Role of Adenosine A1 Receptors in Exogenous Ketone Supplements-Evoked Anti-Epileptic Effect. Int. J. Mol. Sci., 25:9869. (SJR: D1) (2023; IF 4,9) https://doi.org/10.3390/ijms25189869
  2. Rauch, E., Ari, C., D'Agostino, D.P., Kovács, Z. (2024). Exogenous Ketone Supplement Administration Abrogated Isoflurane-Anesthesia-Induced Increase in Blood Glucose Level in Female WAG/Rij Rats. Nutrients, 16:1477. (SJR: D1) (2023; IF 4,8) doi: 10.3390/nu16101477.; https://pubmed.ncbi.nlm.nih.gov/38794716/
  3. Rauch, E., Ari, C., Kovács, Z. (2023). Dose-Dependent Beneficial Effect of Ketone Supplement-Evoked Ketosis on Anxiety Level in Female WAG/Rij Rats: Sometimes Less Is More. Nutrients, 15:4412. (SJR: D1) (IF 4,8) doi: 10.3390/nu15204412. https://www.mdpi.com/2072-6643/15/20/4412
  4. Kovács, Z., D'Agostino, D.P., Ari, C. (2023). Ketone supplementation abolished isoflurane anesthesia-induced elevation in blood glucose level and increased recovery time from anesthesia in Wistar Albino Glaxo Rijswijk rats. BMC Anesthesiol., 23:43. (SJR: Q2) (IF 2,3) doi: 10.1186/s12871-023-02000-8. https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-023-02000-8
  5. Kovács, Z., Skatchkov, S.N., Szabó, Z., Qahtan, S., Méndez-González, M.P., Malpica-Nieves, C.J., Eaton, M.J., Kardos, J., Héja, L. (2022). Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures. Int. J. Mol. Sci., 23, 8191. (SJR: D1) (IF 5,6) https://doi.org/ 10.3390/ijms23158191 https://www.mdpi.com/1422-0067/23/15/8191
  6. Kovács, Z., Skatchkov, S.N., Veh, R.W., Szabó, Z., Németh, K., Szabó, P.T., Kardos, J., Héja, L. (2022). Critical role of astrocytic polyamine and GABA metabolism in epileptogenesis. Font. Cell. Neurosci., 15:787319. (SJR: Q1) (IF 5.3) doi: 10.3389/fncel.2021.787319 https://www.frontiersin.org/articles/10.3389/fncel.2021.787319/full
  7. Brunner, B., Ari, C., D’Agostino, D.P., Kovács, Z. (2021). Adenosine receptors modulate the exogenous ketogenic supplement-evoked alleviating effect on lipopolysaccharide-generated increase in absence epileptic activity in WAG/Rij rats. Nutrients, 13:4082. (SJR: D1) (IF 6.706) doi: 10.3390/nu13114082 https://www.mdpi.com/2072-6643/13/11/4082
  8. Kovács, Z., Brunner, B., Ari, C. (2021). Beneficial effects of exogenous ketogenic supplements on aging processes and age-related neurodegenerative diseases. Nutrients, 13:2197. (SJR: D1) (IF 6.706) doi: 10.3390/nu13072197. https://www.mdpi.com/2072-6643/13/7/2197
  9. Brunner, B., Rauch, E., Ari, C., D’Agostino, D.P., Kovács, Z. (2021). Enhancement of ketone supplements-evoked effect on absence epileptic activity by co-administration of uridine in Wistar Albino Glaxo Rijswijk rats. Nutrients, 13:234. (SJR: D1) (IF 6.706) doi: 10.3390/nu13010234 https://www.mdpi.com/2072-6643/13/1/234
  10. Kovács, Z., Brunner, B., D'Agostino, D.P., Ari, C. (2021). Age- and sex-dependent modulation of exogenous ketone supplement-evoked effects on blood glucose and ketone body levels in Wistar Albino Glaxo Rijswijk rats. Front. Neurosci., 14:618422. (SJR: Q2) (IF 5.152) doi: 10.3389/fnins.2020.618422 https://www.frontiersin.org/articles/10.3389/fnins.2020.618422/full
  11. Ari, C., Murdun, C., Goldhagen, C., Koutnik, A.P., Bharwani, S.R., Diamond, D.M., Kindy, M., D’Agostino, D.P., Kovács, Z. (2020). Exogenous ketone supplements improved motor performance in preclinical rodent models. Nutrients, 12:2459. (SJR: D1) (IF 5.719) doi: 10.3390/nu12082459 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468837/
  12. Kovács, Z., Brunner, B., D'Agostino, D.P., Ari, C. (2020). Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats. BMC Anesthesiol., 20:30. (SJR: Q2) (IF 2.217) doi: 10.1186/s12871-020-0943-z. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993369/
  13. Ari, C., Murdun, C., Koutnik, A.P., Goldhagen, C.R., Rogers, C., Park, C., Bharwani, S., Diamond, D.M., Kindy, M.S., D'Agostino, D.P., Kovács, Z. (2019). Exogenous ketones lower blood glucose level in rested and exercised rodent models. Nutrients, 11:2330. (SJR: D1) (IF 4.546) doi: 10.3390/nu11102330. https://www.mdpi.com/2072-6643/11/10/2330
  14. Kovács, Z., D’Agostino, D.P., Diamond, D., Kindy, M.S., Rogers, C., Ari, C. (2019) Therapeutic potential of exogenous ketone supplement induced ketosis in the treatment of psychiatric disorders: Review of current literature. Front. Psychiatry, 10:363. (SJR: Q1) (IF 2.849) doi: 10.3389/fpsyt.2019.00363 https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00363/full
  15. Ughy, B., Schmidthoffer, I., Szilak, L. (2019). Heparan sulfate proteoglycan (HSPG) can take part in cell division: inside and outside. Cell. Mol. Life Sci., 76:865-871. doi: 10.1007/s00018-018-2964-z. (SJR: Q1) (IF 6.496) https://link.springer.com/article/10.1007/s00018-018-2964-z
  16. Vincze, R., Péter, M., Szabó, Z., Kardos, J., Héja, L., Kovács, Z. (2019) Connexin 43 differentially regulates epileptiform activity in models of convulsive and non-convulsive epilepsies; Front. Cell. Neurosci., 13:173. (SJR: Q2) (IF 3.921) doi: 10.3389/fncel.2019.00173 https://www.frontiersin.org/articles/10.3389/fncel.2019.00173/abstract
  17. Kovács, Z., D'Agostino, D.P., Diamond, D.M., Ari, C. (2019) Exogenous ketone supplementation decreased the lipopolysaccharide-induced increase in absence epileptic activity in Wistar Albino Glaxo Rijswijk rats. Front. Mol. Neurosci., 12:45. (SJR: Q1), (IF 4.057) doi: 10.3389/fnmol.2019.00045 https://www.frontiersin.org/articles/10.3389/fnmol.2019.00045/full
  18. Ari, C., D’Agostino, D.P., Diamond, D.M., Kindy, M., Park, C., Kovács, Z. (2019) Elevated plus maze test combined with video tracking software to investigate the anxiolytic effect of exogenous ketogenic supplements. J. Vis. Exp., 143:e58396. (SJR: Q2), (IF 1.163) doi: 10.3791/58396 https://www.jove.com/video/58396/elevated-plus-maze-test-combined-with-video-tracking-software-to
  19. Penke, B., Paragi, G., Gera, J., Berkecz, R., Kovács, Z., Crul, T., Vígh, L. (2018) The role of lipids and membranes in the pathogenesis of Alzheimer's disease: A comprehensive view. Curr. Alzheimer Res., 15, 1191-1212. (SJR: Q2), (IF 3.271) doi: 10.2174/1567205015666180911151716 http://www.eurekaselect.com/165315/article
  20. Ari C., Kovács Z., Murdun C., Koutnik A.P., Goldhagen C.R., Rogers C., Diamond D., D'Agostino D.P. (2018) Nutritional ketosis delays the onset of isoflurane induced anesthesia. BMC Anesthesiol., 18:85. (SJR: Q2), (IF 1.619) doi: 10.1186/s12871-018-0554-0 https://bmcanesthesiol.biomedcentral.com/track/pdf/10.1186/s12871-018-0554-0
  21. Papp, P., Kovács, Z., Szocsics, P., Juhász, G., Maglóczky, Z. (2018) Alterations in hippocampal and cortical densities of functionally different interneurons in rat models of absence epilepsy. Epilepsy Res., 145, 40–50. (SJR: Q2), (IF 2.178) doi: 10.1016/j.eplepsyres.2018.05.013 https://www.sciencedirect.com/science/article/pii/S0920121118300317
  22. Kovács, Z., D'Agostino, D.P., Ari, C. (2018) Anxiolytic effect of exogenous ketone supplementation is abolished by adenosine A1 receptor inhibition in Wistar Albino Glaxo/Rijswijk rats. Front. Behav. Neurosci., 12:29; (SJR: Q1), (IF 2,622) doi: 10.3389/fnbeh.2018.00029 https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00029/full
  23. Lakatos, R.K., Dobolyi, Á., Kovács, Z. (2018) Uric acid and allopurinol aggravate absence epileptic activity in Wistar Albino Glaxo Rijswijk rats. Brain Res., 1686, 1–9. (SJR: Q1), (IF 2,929) doi: 10.1016/j.brainres.2018.02.012 https://pubmed.ncbi.nlm.nih.gov/29457994/
  24. Barna, J., Renner, É., Arszovszki, A., Cservenák, M., Kovács, Z., Palkovits, M., Dobolyi, A. (2018) Suckling induced activation pattern in the brain of rat pups. Nutr. Neurosci., 21, 317-327. (SJR: Q1), (IF 3.950) doi: 10.1080/1028415X.2017.1286446 https://www.ncbi.nlm.nih.gov/pubmed/28185482
  25. Kovács, Z., D’Agostino, D.P., Dobolyi, A., Ari, C. (2017) Adenosine A1 receptor antagonism abolished the anti-seizure effects of exogenous ketone supplementation in Wistar Albino Glaxo Rijswijk rats. Front. Mol. Neurosci., 10:235. (SJR: Q1), (IF 3.902) doi: 10.3389/fnmol.2017.00235 https://www.frontiersin.org/articles/10.3389/fnmol.2017.00235/full
  26. Kovács, Z., Lakatos, R.K., Barna, J., Dobolyi, A. (2017) Absence epileptic activity in Wistar Albino Glaxo Rijswijk rat mothers. Brain Res., 1657, 368–376. (SJR: Q1), (IF 3.125) doi: 10.1016/j.brainres.2017.01.005 https://www.sciencedirect.com/science/article/pii/S0006899317300057
  27. Ari, C., Kovacs, Z., Juhasz, G., Murdun, C., Goldhagen, C.R., Koutnik, A.P., Poff, A.M., Kesl, S.L., D'Agostino, D.P. (2016) Exogenous ketone supplements reduce anxiety-related behavior in Sprague-Dawley and Wistar Albino Glaxo/Rijswijk rats. Front. Mol. Neurosci., 9:137. (SJR: Q1), (IF 5.076) doi: 10.3389/fnmol.2016.00137 http://journal.frontiersin.org/article/10.3389/fnmol.2016.00137/abstract
  28. Lakatos, R.K., Dobolyi, Á., Todorov, M.I., Kékesi, K.A., Juhász, G., Aleksza, M., Kovács, Z. (2016) Guanosine may increase absence epileptic activity by means of A2A adenosine receptors in Wistar Albino Glaxo Rijswijk rats. Brain Res. Bull., 124, 172-181. (SJR: Q2), (IF 3.033) doi: 10.1016/j.brainresbull.2016.05.001 http://www.sciencedirect.com/science/article/pii/S0361923016300971
  29. Kovács, Z., Kékesi, K.A., Juhász, G., Dobolyi, A. (2015) Modulatory effects of inosine, guanosine and uridine on lipopolysaccharide-evoked increase in spike-wave discharge activity in Wistar Albino Glaxo/Rijswijk rats. Brain Res. Bull., 118, 46-57. (SJR: Q2), (IF 2.572) doi: 10.1016/j.brainresbull.2015.09.003 http://www.sciencedirect.com/science/article/pii/S0361923015300319
  30. Volgyi, K., Juhasz, G., Kovács, Z., Penke, B. (2015) Dysfunction of endoplasmic reticulum (ER) and mitochondria (MT) in Alzheimer's disease: The role of the ER-MT cross-talk. Curr. Alz. Res., 12, 655-672. (SJR: Q1), (IF 3.145) doi: 10.2174/1567205012666150710095035 http://www.eurekaselect.com/132975/article
  31. Kovács, Z., Kékesi, K.A., Dobolyi, Á., Lakatos, R., Juhász, G. (2015) Absence epileptic activity changing effects of non-adenosine nucleoside inosine, guanosine and uridine in Wistar Albino Glaxo Rijswijk rats. Neuroscience, 300, 593-608. (SJR: Q2), (IF 3.231) doi: 10.1016/j.neuroscience.2015.05.054 http://www.sciencedirect.com/science/article/pii/S0306452215004960
  32. Kovács, Z., Kardos, J., Kékesi, K.A., Juhász, G., Lakatos, R., Héja, L. (2015) Effects of nucleosides on glia - neuron interactions open up new vistas in development of more effective antiepileptic drugs. Curr. Med. Chem., 22, 1500-1514. (SJR: Q2), (IF 3.455) doi: 10.2174/0929867322666150212153210 http://www.eurekaselect.com/128427/article
  33. Kovács, Z., Kékesi, K.A., Juhász, G., Barna, J., Héja, L., Lakatos, R., Dobolyi, Á. (2015) Non-adenosine nucleoside inosine, guanosine and uridine as promising antiepileptic drugs: a summary of current literature. Mini Rev. Med. Chem., 14, 1033-1042. (SJR: Q2), (IF 2.841) doi: 10.2174/1389557514666141107120226 http://www.eurekaselect.com/125918/article
  34. Kovács, Z., Kékesi, K. A., Juhász, G., Dobolyi, A. (2014) The antiepileptic potential of nucleosides. Curr. Med. Chem., 21, 788-821. (SJR: Q1), (IF 3.853) doi: 10.2174/1381612819666131119154505 http://www.eurekaselect.com/118147/article
  35. Dobolyi, A., Kékesi, K. A., Juhász. G., Székely, A. D., Lovas, G., Kovács, Z. (2014) Receptors of peptides as therapeutic targets in epilepsy research. Curr. Med. Chem., 21, 764-787. (SJR: Q1), (IF 3.853) doi: 10.2174/0929867320666131119154018 http://www.eurekaselect.com/118146/article
  36. Györffy, B., Kovács, Z., Gulyássy, P., Simor, A., Völgyi, K., Orbán, G., Baracskay, P., Szabó, Z., Janáky, T., Dobolyi, Á., Juhász, G., Czurkó, A., Kékesi, K.A. (2014) Brain protein expression changes in WAG/Rij rats, a genetic rat model of absence epilepsy after peripheral lipopolysaccharide treatment. Brain. Behav. Immun., 35, 86-95. (SJR: D1), (IF: 5.889) doi: 10.1016/j.bbi.2013.09.001 http://www.sciencedirect.com/science/article/pii/S0889159113004509
  37. Kovács, Z., Dobolyi, Á., Juhász, G., Kékesi, K.A. (2014) Lipopolysaccharide induced increase in seizure activity in two animal models of absence epilepsy WAG / Rij and GAERS rats and Long Evans rats. Brain Res. Bull., 104, 7-18. (SJR: Q2), (IF: 2.718) doi: 10.1016/j.brainresbull.2014.03.003 http://www.sciencedirect.com/science/article/pii/S0361923014000392
  38. Danyadi, B., Szabadfi, K., Reglodi, D., Mihalik, A., Danyadi, T., Kovács, Z., Batai, I., Tamas, A., Kiss, P., Toth, G., Gabriel, R. (2014) PACAP application improves functional outcome of chronic retinal ischemic injury in rats - evidence from electroretinographic measurements. J. Mol. Neurosci., 54, 293-299. (SJR: Q1), (IF: 2.343) doi: 10.1007/s12031-014-0296-5 http://link.springer.com/article/10.1007%2Fs12031-014-0296-5
  39. Kovács, Z., Dobolyi, A., Kékesi, K. A., Juhász. G. (2013) 5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications. Curr. Med. Chem., 20, 4217-4240. (SJR: Q1), (IF 3.715) doi: 10.2174/0929867311320340003 http://www.eurekaselect.com/116019/article
  40. Kovács, Z., Slézia, A., Bali, Z. K., Kovács, P., Dobolyi, Á., Szikra, T., Hernádi, I., Juhász. G. (2013) Uridine modulates neuronal activity and inhibits spike-wave discharges of absence epileptic Long Evans and Wistar Albino Glaxo/Rijswijk rats. Brain Res. Bull., 97, 16-23. (SJR: Q2), (IF 2.974) doi: 10.1016/j.brainresbull.2013.05.009 http://www.sciencedirect.com/science/article/pii/S0361923013000919
  41. Kovács, Z., Czurkó, A., Kékesi, K. A., Juhász, G. (2012) Neonatal tricyclic antidepressant clomipramine treatment reduces the spike-wave discharge activity of the adult WAG/Rij rat. Brain Res. Bull., 89, 102-107. (SJR: Q2), (IF 2.935) doi: 10.1016/j.brainresbull.2012.07.010 http://www.sciencedirect.com/science/article/pii/S0361923012001797
  42. Kovács, Z., Kékesi, K. A., Baracskay, P., Juhász, G., Czurkó, A. (2011) Doxycycline could aggravate the absence-like epileptic seizures of WAG/Rij rats via matrix metalloproteinase inhibition. Neurochem. Int., 59, 563-566. (SJR: Q2), (IF 2.857) doi: 10.1016/j.neuint.2011.06.016 http://www.sciencedirect.com/science/article/pii/S0197018611002129
  43. Kovács, Z., Czurkó, A., Kékesi, K. A., Juhász, G. (2011) Intracerebroventricularly administered lipopolysaccharide enhances spike-wave discharges in freely moving WAG/Rij rats. Brain Res. Bull., 85, 410-416. (SJR: Q2), (IF 2.818) doi: 10.1016/j.brainresbull.2011.05.003 http://www.sciencedirect.com/science/article/pii/S0361923011001468
  44. Kovács, Z., Czurkó, A., Kékesi, K. A., Juhász, G. (2011). The effect of intraperitoneally administered dimethyl sulfoxide on absence-like epileptic activity of freely moving WAG/RIJ rats. J. Neurosci. Methods, 197, 133-136. (SJR: Q2), (IF 1.98) doi: 10.1016/j.jneumeth.2011.02.005 http://www.sciencedirect.com/science/article/pii/S016502701100080X
  45. Kovács, Z., Juhász, G., Palkovits, M., Dobolyi, Á., Kékesi, KA. (2011) Area, age and gender dependence of the nucleoside system in the brain: A review of current literature. Curr. Top. Med. Chem., 11, 1012-1033. (SJR: Q1), (IF 4.174) doi: 10.2174/156802611795347636 http://www.ncbi.nlm.nih.gov/pubmed/21401498
  46. Dobolyi, Á., Juhász, G., Kovács, Z., Kardos, J. (2011) Uridine function in the central nervous system. Curr. Top. Med. Chem., 11, 1058-1067. (SJR: Q1), (IF 4.174) doi: 10.2174/156802611795347618 http://www.ncbi.nlm.nih.gov/pubmed/21401495
  47. Takács, E., Nyilas, R., Szepesi, Z., Baracskay, P., Karlsen, B., Røsvold, T., Bjørkum, A. A., Czurkó, A., Kovács, Z., Kékesi, A. K., Juhász, G. (2010). Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: a possible role in homeostatic synaptic plasticity. Neurochem. Int., 56, 799-809. (SJR: Q2), (IF 3.601) doi: 10.1016/j.neuint.2010.03.003 http://www.ncbi.nlm.nih.gov/pubmed/20303372
  48. Kovács, Z., Czurkó, A., Kékesi, K. A., Juhász, G. (2010). Clomipramine increases the incidence and duration of spike-wave discharges in freely moving WAG/Rij rats. Epilepsy Res., 90, 167-170. (SJR: Q2), (IF 2.302) doi: 10.1016/j.eplepsyres.2010.02.011 http://www.ncbi.nlm.nih.gov/pubmed/20299188
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